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Chemistry 12 · Chemistry · Lesson 5.2

The chemistry of buffers

Level
Grade 12
Reading time
11 min reading
Review
Last reviewed 2026-09-03
Errata

Abstract

Solutions that resist changes in pH.

What is a buffer solution?

Short answer

A buffer is a solution that resists changes in pH when small amounts of acid or base are added. It contains a weak acid and its conjugate base (or a weak base and its conjugate acid) in comparable amounts; one component neutralizes added base and the other neutralizes added acid. Buffers keep systems like blood at a nearly constant pH.

Concept preview

What you will be able to do

  1. 01Explain how a buffer resists a change in pH
  2. 02Use the Henderson-Hasselbalch equation to find or design a buffer pH
  3. 03Explain buffer capacity

Some solutions hold their pH almost constant even when acid or base is added; these are buffers. A buffer is a mixture of a weak acid and its conjugate base (or a weak base and its conjugate acid), present together in comparable amounts. The essential requirement is that both members of a conjugate pair be present in significant quantities — one to neutralise added base, and the other to neutralise added acid.

School Plan

The chemistry of buffers

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Related topics

Frequently asked questions

How does a buffer resist pH change?
Its weak-acid component neutralizes added base and its conjugate-base component neutralizes added acid, keeping [H⁺] nearly constant.
Why is blood a buffered solution?
The carbonic acid–bicarbonate buffer keeps blood pH near 7.4, which is essential for enzyme and cell function.